Therefore, analysis of cancer-derived EVs might indicate the presence and nature of cancer. In particular, cancer-derived EVs contain cancer-specific molecules expressed in parental cancer cells. The molecular contents of EVs largely reflect the cell of origin and thus show cell-type specificity. EVs carry complex molecular cargoes, such as proteins, RNAs, and DNA fragments these cargoes are delivered to recipient cells and serve as a cell-to-cell communication system. Extracellular vesicles (EVs) are lipid membranous vesicles released from almost all cell types, and they represent a novel liquid biopsy resource. Liquid biopsy has considerable clinical application potential, such as in early diagnosis, pathological condition monitoring, and tailored treatment development based on cancer biology and the predicted treatment response of individual patients. Liquid biopsy is a minimally invasive biopsy method that uses molecules in body fluids as biomarkers, and it has attracted attention as a new cancer therapy tool.
